TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia
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DOI: 10.1080/15548627.2018.1556946
Abstract: ABSTRACT Macroautophagy/autophagy is a lysosome-dependent catabolic process for the turnover of proteins and organelles in eukaryotes. Autophagy plays an important role in immunity and inflammation, as well as metabolism and cell survival. Diverse immune and… read more here.
Keywords: capacity microglia; toll like; autophagy inhibition; foxo3 ... See more keywords