Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase
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DOI: 10.1126/science.aav0080
Abstract: A cap-specific m6A writer N6,2′-O-dimethyladenosine (m6Am) is present at the transcription start nucleotide of capped mRNAs in vertebrates. Akichika et al. quantified the abundance of this modification in the transcriptome and identified the writer protein,… read more here.
Keywords: methylation; capped mrnas; m6am; cap specific ... See more keywords