Engineering an Fc-Fusion of a Capsule Degrading Enzyme for the Treatment of Anthrax.
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DOI: 10.1021/acsinfecdis.2c00227
Abstract: Polymers of d-glutamic acid (PDGA) form the capsule of the highly virulent Ames strain of B. anthracis. PDGA is antiphagocytic and weakly immunogenic; it enables the bacteria to evade the innate immune responses. CapD is an… read more here.
Keywords: fusion; mpeg; thr 352; capds334c ... See more keywords