Defining the Caprin-1 Interactome in Unstressed and Stressed Conditions.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00016
Abstract: Cytoplasmic stress granules (SGs) are dynamic foci containing translationally arrested mRNA and RNA-binding proteins (RBPs) that form in response to a variety of cellular stressors. It has been debated that SGs may evolve into cytoplasmic… read more here.
Keywords: stressed conditions; caprin; caprin interactome; interactome unstressed ... See more keywords
Yin and yang regulation of stress granules by Caprin-1
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2207975119
Abstract: Significance Stress granules (SGs) are membraneless organelles regulating many vital biochemical processes. G3BP1 plays a critical role in regulating SG dynamics through its interaction with Caprin-1 and USP10. The crystal structures of the NTF2L domain… read more here.
Keywords: stress granules; regulation stress; yang regulation; caprin ... See more keywords
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH
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DOI: 10.1098/rsob.220369
Abstract: G3BP is the central node within stress-induced protein–RNA interaction networks known as stress granules (SGs). The SG-associated proteins Caprin-1 and USP10 bind mutually exclusively to the NTF2 domain of G3BP1, promoting and inhibiting SG formation,… read more here.
Keywords: caprin binding; caprin; g3bp1; binding critical ... See more keywords