Antiviral activity of Α-hydroxytropolones on caprine alphaherpesvirus 1 in vitro.
Sign Up to like & getrecommendations! Published in 2020 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2020.01.011
Abstract: The emergence of human alphaherpesvirus strains (i.e. HHV-1 and -2) resistant to commonly used antiviral drugs has prompted the research for alternative, biologically active anti-herpetic agents. Natural-product and synthetic α-hydroxytropolones (αHTs) have been identified as… read more here.
Keywords: caprine alphaherpesvirus; antiviral activity; hydroxytropolones caprine; activity hydroxytropolones ... See more keywords
Deletion of the thymidine kinase gene attenuates Caprine alphaherpesvirus 1 in goats.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2019.07.022
Abstract: Caprine alphaherpesvirus 1 (CpHV-1) is a pathogen associated with systemic infection and respiratory disease in kids and subclinical infection or reproductive failure and abortions in adult goats. The enzyme thymidine kinase (TK) is an important… read more here.
Keywords: caprine alphaherpesvirus; cphv; gene; virus ... See more keywords