Role of capsaicin sensitive sensory nerves in ischemia reperfusion-induced acute kidney injury in rats.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.10.061
Abstract: Acute kidney injury (AKI) is a common kidney disorder which is associated with a high risk of mortality. Extensive evidence revealed the participation of renal afferent sensory nerves in the pathophysiology of renal ischemia reperfusion… read more here.
Keywords: sensory nerves; capsaicin sensitive; injury; degeneration ... See more keywords
Capsaicin-sensitive cutaneous primary afferents convey electrically induced itch in humans
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.11.061
Abstract: Specially designed transcutaneous electrical stimulation paradigms can be used to provoke experimental itch. However, it is unclear which primary afferent fibers are activated and whether they represent pathophysiologically relevant, C-fiber mediated itch. Since low-threshold mechano-receptors… read more here.
Keywords: itch; stimulation; capsaicin sensitive; primary afferent ... See more keywords
Nerve growth factor‐dependent hyperexcitability of capsaicin‐sensitive bladder afferent neurones in mice with spinal cord injury
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Physiology"
DOI: 10.1113/ep086951
Abstract: What is the central question of this study? Nerve growth factor (NGF) is reportedly a mediator inducing urinary bladder dysfunction. Is NGF directly involved in hyperexcitability of capsaicin‐sensitive C‐fibre bladder afferent pathways after spinal cord… read more here.
Keywords: bladder afferent; hyperexcitability capsaicin; bladder; capsaicin sensitive ... See more keywords
Desensitization of Capsaicin-Sensitive Afferents Accelerates Early Tumor Growth via Increased Vascular Leakage in a Murine Model of Triple Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.685297
Abstract: There is growing interest in the role of nerve-driven mechanisms in tumorigenesis and tumor growth. Capsaicin-sensitive afferents have been previously shown to possess antitumoral and immune-regulatory properties, the mechanism of which is currently poorly understood.… read more here.
Keywords: tumor; capsaicin sensitive; sensitive afferents; breast cancer ... See more keywords
The Mysteries of Capsaicin-Sensitive Afferents
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.554195
Abstract: A fundamental subdivision of nociceptive sensory neurons is named after their unique sensitivity to capsaicin, the pungent ingredient in hot chili peppers: these are the capsaicin-sensitive afferents. The initial excitation by capsaicin of these neurons… read more here.
Keywords: trpv1; capsaicin sensitive; mysteries capsaicin; sensitive afferents ... See more keywords