Lenacapavir and the novel HIV-1 capsid inhibitors: an emerging therapy in the management of multidrug-resistant HIV-1 virus
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DOI: 10.1097/qco.0000000000000896
Abstract: Purpose of review The aim of this study was to summarize current evidence regarding lenacapavir, a first in class HIV-1 capsid inhibitor, and its role as an emergent therapy for the treatment of HIV-1 infection.… read more here.
Keywords: hiv; hiv capsid; capsid inhibitors; therapy ... See more keywords
Cell Type-Dependent Escape of Capsid Inhibitors by Simian Immunodeficiency Virus SIVcpz
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DOI: 10.1128/jvi.01338-20
Abstract: HIV-1 originated from SIVcpzPtt but not from the related virus SIVcpzPts, and thus, it is important to describe molecular infection by SIVcpzPts in human cells to understand the zoonosis of SIVs. Pharmacological HIV-1 capsid inhibitors… read more here.
Keywords: capsid; hela cells; pf74; virus ... See more keywords