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Published in 2019 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-019-09881-3
Abstract: Enterococcus faecium (E. faecium) has emerged as one of today’s leading causes of health care-associated infections that is difficult to treat with the available antibiotics. These pathogens produce capsular polysaccharides on the cell surface which… read more here.
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Published in 2021 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-021-10000-4
Abstract: The capsular polysaccharide of the human pathogen Group B Streptococcus is a key virulence factor and vaccine candidate that induces protective antibodies when conjugated to carrier proteins. It consists of long polymeric chains of oligosaccharide… read more here.
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Published in 2017 at "Carbohydrate research"
DOI: 10.1016/j.carres.2017.05.017
Abstract: Capsular polysaccharides were isolated from A. baumannii LUH5535 (K35 CPS) and LUH5554 (K15 CPS) and studied by 1D and 2D 1H and 13C NMR spectroscopy. The CPSs were found to consist of linear tetrasaccharide repeats (K… read more here.
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Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113670
Abstract: Capsular polysaccharides of Streptococcus pneumoniae are key components of commercially available anti-pneumococcal vaccines; meanwhile C-polysaccharide is considered an impurity. World Health Organization recommends a strict control over the presence of this biomolecule due to the… read more here.
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Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00096
Abstract: Many strains of Campylobacter jejuni display modified heptose residues in their capsular polysaccharides (CPS). The precursor heptose was previously shown to be GDP-D-glycero-α-D-manno-heptose, from which a variety of modifications to the sugar moiety have been… read more here.
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Published in 2023 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.3c00072
Abstract: Capsule is one of the common virulence factors in Gram-negative bacteria protecting pathogens from host defenses and consists of long-chain capsular polysaccharides (CPS) anchored in the outer membrane (OM). Elucidating structural properties of CPS is… read more here.
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Published in 2020 at "Nature microbiology"
DOI: 10.1038/s41564-020-0746-5
Abstract: A variety of cell surface structures dictate interactions between bacteria and their environment, including their viruses (bacteriophages). Members of the human gut Bacteroidetes characteristically produce several phase-variable capsular polysaccharides (CPSs), but their contributions to bacteriophage… read more here.
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Published in 2018 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2018.00145
Abstract: Pneumonia caused by Streptococcus pneumoniae is a major bacterial disease responsible for many deaths worldwide each year and is particularly dangerous in children under 5 years old and adults over 50. The capsular polysaccharide (CPS)… read more here.
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Published in 2017 at "Pathogens"
DOI: 10.3390/pathogens6020016
Abstract: Streptococcus suis and group B Streptococcus (GBS) are encapsulated streptococci causing septicemia and meningitis. Antibodies (Abs) against capsular polysaccharides (CPSs) have a crucial protective role, but the structure/composition of the CPS, including the presence of… read more here.
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Published in 2019 at "Vaccines"
DOI: 10.3390/vaccines7010018
Abstract: Bacterial pathogens expressing capsular polysaccharides are common causes of mucosal infections (pneumonia, intestinal), as well as often fatal, invasive infections (meningitis, bloodstream infections) in children and adults worldwide. These chemically simple but structurally complex carbohydrate… read more here.