Articles with "capsular switching" as a keyword



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A multiple drug-resistant Streptococcus pneumoniae of serotype 15A occurring from serotype 19A by capsular switching.

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Published in 2020 at "Vaccine"

DOI: 10.1016/j.vaccine.2020.05.075

Abstract: Streptococcus pneumoniae is a highly recombinogenic pathogen. The ability of pneumococci to acquire and incorporate exogenous DNA is an important evolutionary mechanism for adaptation to clinical interventions such as antibiotic therapy and vaccination. Herein, using… read more here.

Keywords: serotype 15a; multiple drug; capsular switching; drug resistant ... See more keywords

A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa

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Published in 2019 at "Journal of Antimicrobial Chemotherapy"

DOI: 10.1093/jac/dkz477

Abstract: Abstract Objectives We reported tet(S/M) in Streptococcus pneumoniae and investigated its temporal spread in relation to nationwide clinical interventions. Methods We whole-genome sequenced 12 254 pneumococcal isolates from 29 countries on an Illumina HiSeq sequencer. Serotype,… read more here.

Keywords: south africa; cc230; capsular switching; tet positive ... See more keywords