Histoplasma Capsulatum: Mechanisms for Pathogenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2018_114
Abstract: Histoplasmosis, caused by the dimorphic environmental fungus Histoplasma capsulatum, is a major mycosis on the global stage. Acquisition of the fungus by mammalian hosts can be clinically silent or it can lead to life-threatening systemic… read more here.
Keywords: mechanisms pathogenesis; capsulatum mechanisms; disease; capsulatum ... See more keywords
Improved serodiagnosis of histoplasmosis by use of deglycosylated extracellular released antigens of Histoplasma capsulatum.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2020.105981
Abstract: The diagnosis of histoplasmosis depends on various approaches: direct clinical examination, fungus isolation from cultures of clinical samples, histopathological evaluation, and serological testing. In serodiagnostic assays, the Histoplasma capsulatum H and M antigenic glycoproteins have… read more here.
Keywords: cross reactivity; capsulatum; extracellular released; deglycosylated extracellular ... See more keywords
Diagnostic d’une histoplasmose disséminée par amplification d’ADN obtenu à partir d’un frottis sanguin
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DOI: 10.1016/j.mycmed.2017.04.076
Abstract: L’histoplasmose humaine existe en Afrique sous ces 2 formes dues respectivement a H. capsulatum var capsulatum et H. capsulatum var duboisii . En Afrique de l’Ouest, la seconde semble predominante. Nous rapportons ici un cas d’histoplasmose disseminee due… read more here.
Keywords: frottis; par; frottis sanguin; capsulatum var ... See more keywords
Histoplasmose africaine : difficultés de prise en charge : à propos de 2 cas diagnostiques au Bénin
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DOI: 10.1016/j.mycmed.2017.04.077
Abstract: L’histoplasmose est une mycose systemique rare causee par deux champignons, Histoplasma capsulatum var capsulatum et Histoplasma capsulatum var duboisii qui sevit en Afrique. Nous rapportons deux cas d’histoplasmoses disseminees a Histoplasma capsulatum var. duboissii diagnostiques… read more here.
Keywords: africaine difficult; cas; capsulatum var; histoplasmose africaine ... See more keywords
Pathogenicity & virulence of Histoplasma capsulatum - A multifaceted organism adapted to intracellular environments
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DOI: 10.1080/21505594.2022.2137987
Abstract: ABSTRACT Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma capsulatum. Although healthy individuals can develop histoplasmosis, the disease is particularly life-threatening in immunocompromised patients, with a wide range of clinical manifestations… read more here.
Keywords: histoplasma capsulatum; virulence; pathogenicity virulence; virulence histoplasma ... See more keywords
A matrix-assisted laser desorption/ionization time of flight mass spectrometry reference database for the identification of Histoplasma capsulatum
Sign Up to like & getrecommendations! Published in 2018 at "Medical Mycology"
DOI: 10.1093/mmy/myx047
Abstract: The isolation of the pathogenic fungus Histoplasma capsulatum from cultures together with the visualization of typical intracellular yeast in tissues are the gold standard methods for diagnosis of histoplasmosis. However, cultures are time-consuming, require level… read more here.
Keywords: time; database; capsulatum; reference database ... See more keywords
L-tyrosine induces the production of a pyomelanin-like pigment by the parasitic yeast-form of Histoplasma capsulatum.
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DOI: 10.1093/mmy/myx068
Abstract: Melanization of Histoplasma capsulatum remains poorly described, particularly in regards to the forms of melanin produced. In the present study, 30 clinical and environmental H. capsulatum strains were grown in culture media with or without… read more here.
Keywords: pyomelanin; yeast; capsulatum; histoplasma capsulatum ... See more keywords
Media Matters! Alterations in the loading and release of Histoplasma capsulatum extracellular vesicles in response to different nutritional milieus.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular microbiology"
DOI: 10.1111/cmi.13217
Abstract: Histoplasma capsulatum is a dimorphic fungus that most frequently causes pneumonia, but can also disseminate and proliferate in diverse tissues. H. capsulatum has a complex secretion system that mediates the release of macromolecule-degrading enzymes and… read more here.
Keywords: extracellular vesicles; response; capsulatum; histoplasma capsulatum ... See more keywords
Histoplasma capsulatum Complement Fixation and Immunodiffusion Assay Sensitivity in Culture-Confirmed Cases of Histoplasmosis: a 10-Year Retrospective Review (2011 to 2020)
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01057-22
Abstract: The detection of antibodies against Histoplasma capsulatum remains a frequently relied-on approach to diagnose histoplasmosis. We retrospectively assessed the performances of complement fixation (CF) and immunodiffusion (ID) assays for anti-Histoplasma antibody detection in patients with… read more here.
Keywords: culture confirmed; histoplasma capsulatum; complement fixation; fixation immunodiffusion ... See more keywords
Primary Cutaneous Histoplasma capsulatum Infection in a Patient Treated With Fingolimod: A Case Report
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DOI: 10.1177/1203475417719043
Abstract: Fingolimod is an immune-modulating drug used in the treatment of multiple sclerosis. Histoplasma capsulatum is a dimorphic fungus that can infect humans. Infection with the pathogen typically affects the lungs, but it is usually asymptomatic… read more here.
Keywords: patient treated; infection patient; primary cutaneous; capsulatum ... See more keywords
Prostaglandins D2 and E2 have opposite effects on alveolar macrophages infected with Histoplasma capsulatum[S]
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Lipid Research"
DOI: 10.1194/jlr.m078162
Abstract: Prostaglandin E2 (PGE2) suppresses macrophage effector mechanisms; however, little is known about the function of PGD2 in infected alveolar macrophages (AMs). Using serum-opsonized Histoplasma capsulatum (Ops-H. capsulatum) in vitro, we demonstrated that AMs produced PGE2… read more here.
Keywords: prostaglandins opposite; alveolar macrophages; pge2; opposite effects ... See more keywords