Poly(lactic-co-glycolic) Acid as a Slow-Release Drug-Carrying Matrix for Methotrexate Coated onto Intraocular Lenses to Conquer Posterior Capsule Opacification
Sign Up to like & getrecommendations! Published in 2018 at "Current Eye Research"
DOI: 10.1080/02713683.2018.1437455
Abstract: ABSTRACT Purpose: Posterior capsule opacification (PCO) still represents the main long-term complication of cataract surgery. Research into pharmacologic PCO prophylaxis is extensive. One promising candidate drug is methotrexate (MTX). Our aim is to determine the… read more here.
Keywords: poly lactic; posterior capsule; drug; mtx ... See more keywords
Inhibition of posterior capsule opacification by adenovirus-mediated delivery of short hairpin RNAs targeting TERT in a rabbit model.
Sign Up to like & getrecommendations! Published in 2023 at "Current eye research"
DOI: 10.1080/02713683.2023.2194587
Abstract: PURPOSE Posterior capsule opacification (PCO) is the most common postoperative complication after cataract surgery and cannot yet be eliminated. Here, we investigated the inhibitory effects of telomerase reverse transcriptase (TERT) gene silencing on PCO in… read more here.
Keywords: capsule opacification; posterior capsule; hairpin rnas; rabbit model ... See more keywords
Effect of femtosecond laser‐assisted lens surgery on posterior capsule opacification in the human capsular bag in vitro
Sign Up to like & getrecommendations! Published in 2017 at "Acta Ophthalmologica"
DOI: 10.1111/aos.13103
Abstract: To compare posterior capsule opacification (PCO) by observing lens epithelial cell growth in the human capsular bag in vitro between conventional lens surgery using phacoemulsification (Phaco) technique and femtosecond laser‐assisted lens surgery (FLACS). read more here.
Keywords: surgery; capsular bag; posterior capsule; human capsular ... See more keywords
Dynamic changes of Elschnig pearls posterior capsule opacification
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DOI: 10.1136/bcr-2021-248259
Abstract: An adolescent female with underlying bilateral pseudophakia and idiopathic intermediate uveitis had reduced visual acuity due to posterior capsule opacification (PCO). The rapid progression and different morphological formations of Elschnig pearls were not influenced by… read more here.
Keywords: elschnig pearls; posterior capsule; dynamic changes; capsule opacification ... See more keywords
Acute retinal detachment after Nd:YAG treatment for vitreous floaters and postertior capsule opacification: a case report
Sign Up to like & getrecommendations! Published in 2020 at "BMC Ophthalmology"
DOI: 10.1186/s12886-020-01428-7
Abstract: Background Modern laser surgery uses Nd:YAG laser capsulotomy for posterior capsule opacification (PCO) and Nd:YAG laser vitreolysis for symptomatic vitreous floaters (VF). We report a case of acute retinal detachment seven days after Nd:YAG laser… read more here.
Keywords: case; yag; retinal detachment; capsule opacification ... See more keywords
Celastrol-based nanomedicine hydrogels eliminate posterior capsule opacification.
Sign Up to like & getrecommendations! Published in 2022 at "Nanomedicine"
DOI: 10.2217/nnm-2022-0191
Abstract: Aim: To formulate an injectable thermosensitive micelle-hydrogel hybrid system loaded with celastrol (celastrol-loaded micelle hydrogel: CMG) to prevent posterior capsule opacification (PCO). Materials & methods: Celastrol-loaded micelles were embedded in a thermosensitive hydrogel matrix to… read more here.
Keywords: capsule opacification; hydrogel; posterior capsule; capsule ... See more keywords
Clinical Translation of Long-Acting Drug Delivery Systems for Posterior Capsule Opacification Prophylaxis
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15041235
Abstract: Posterior capsule opacification (PCO) remains the most common cause of vision loss post cataract surgery. The clinical management of PCO formation is limited to either physical impedance of residual lens epithelial cells (LECs) by implantation… read more here.
Keywords: capsule opacification; posterior capsule; drug delivery; long acting ... See more keywords
Impact of anterior capsular polishing on capsule opacification rate in eyes undergoing femtosecond laser-assisted cataract surgery
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_1787_19
Abstract: Purpose: To evaluate the impact of anterior capsular polishing on capsule opacification and contraction in eyes undergoing femtosecond laser-assisted cataract surgery (FLACS). Methods: This prospective interventional comparative analysis included patients undergoing FLACS between August 2016… read more here.
Keywords: capsular polishing; opacification; polishing capsule; capsule opacification ... See more keywords
CTGF Contributes to the Development of Posterior Capsule Opacification: an in vitro and in vivo study
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DOI: 10.7150/ijbs.23946
Abstract: Connective tissue growth factor (CTGF) is a crucial factor that plays a major role in the process of posterior capsule opacification (PCO). However, the effects of CTGF on the proliferation and migration of lens epithelial… read more here.
Keywords: posterior capsule; expression; ctgf; development ... See more keywords