Hydrogen-Deuterium Exchange and Electron Capture Dissociation to Interrogate the Conformation of Gaseous Melittin Ions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of The American Society for Mass Spectrometry"
DOI: 10.1007/s13361-019-02150-5
Abstract: AbstractThere is a need in the field of biological mass spectrometry for structural tools which can report on regional, rather than solely global, structure of gaseous protein ions. Site-specific hydrogen-deuterium (H/D) exchange has shown promise… read more here.
Keywords: capture dissociation; electron capture; exchange electron; melittin ... See more keywords
Native Electron Capture Dissociation Maps to Iron-Binding Channels in Horse Spleen Ferritin
Sign Up to like & getrecommendations! Published in 2017 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.7b01581
Abstract: Native electron capture dissociation (NECD) is a process during which proteins undergo fragmentation similar to that from radical dissociation methods, but without the addition of exogenous electrons. However, after three initial reports of NECD from… read more here.
Keywords: capture dissociation; electron capture; dissociation; iron binding ... See more keywords
Peptide Sequence Influence on the Differentiation of Valine and Norvaline by Hot Electron Capture Dissociation.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b04808
Abstract: Isomeric amino acid residues such as valine (Val) and norvaline (Nva) are common in recombinant proteins. The mis-incorporation of Nva for leucine (Leu) causes heterogeneity and in some cases even toxicity. Previous studies have shown… read more here.
Keywords: capture dissociation; hot electron; electron capture;
Achieving Electron Capture Dissociation in the Radio Frequency Linear Ion Trap without the Assistance of a Magnetic Field─A Simulation Study.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.4c00287
Abstract: It is extremely difficult to inject a low-energy electron beam into a conventional radiofrequency (RF) linear ion trap for electron capture dissociation (ECD) without using a magnetic field to focus the electrons. In this study,… read more here.
Keywords: capture dissociation; linear ion; electron capture; ion trap ... See more keywords