Protein A and CaptureSelect FcXP Affinity Resins Possess the Capability of Differentiating Hole-hole Homodimer Isoforms.
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DOI: 10.2174/0929866530666230516122012
Abstract: BACKGROUND Knobs-into-holes (KiH) technology has been widely used in asymmetric bispecific antibody (bsAb) construction to promote heavy chain heterodimerization. However, despite the great improvement of heterodimer formation by this strategy, homodimers (especially the hole-hole homodimer)… read more here.
Keywords: captureselect fcxp; affinity; hole hole; hole homodimer ... See more keywords