Abstract 2711: Repurposing CAR targets in solid tumors from pan-cancer single-cell RNA-seq data
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/1538-7445.am2022-2711
Abstract: Chimeric antigen receptor (CAR) T cell therapy is a powerful and promising tool for unleashing lasting antitumor immunity, which is currently studied in numerous blood and solid cancers. Here, mining single cell transcriptomics datasets of… read more here.
Keywords: car; single cell; solid tumors; car targets ... See more keywords
Abstract LB062: Identifying novel targets for CAR-T therapies from single cell RNA-sequencing data
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb062
Abstract: Chimeric antigen receptor T (CAR-T) cell therapies have revolutionized cancer treatment. While CAR-T has yielded tremendous clinical success for patients with liquid tumors, its potential remains to be unleashed against solid tumors. One key challenge… read more here.
Keywords: cell; identifying novel; novel targets; car ... See more keywords