Synthesis and evaluation of carbamate derivatives as fatty acid amide hydrolase and monoacylglycerol lipase inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200081
Abstract: Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) are the primary catabolic enzymes for endocannabinoids, anandamide (AEA), and 2‐arachidonoyl glycerol. Numerous studies have shown that FAAH and MAGL play an important role in modulating… read more here.
Keywords: faah magl; acid amide; carbamate; fatty acid ... See more keywords
Advanced Pyrrolidine‐Carbamate Self‐Immolative Spacer with Tertiary Amine Handle Induces Superfast Cyclative Drug Release
Sign Up to like & getrecommendations! Published in 2022 at "Chemmedchem"
DOI: 10.1002/cmdc.202200279
Abstract: Amine‐carbamate self‐immolative (SI) spacers represent practical and versatile tools in targeted prodrugs, but their slow degradation mechanism limits drug activation at the site of disease. We engineered a pyrrolidine‐carbamate SI spacer with a tertiary amine… read more here.
Keywords: pyrrolidine carbamate; self immolative; spacer; spacer tertiary ... See more keywords
Analysis of ethyl carbamate in plum wines produced in Korea
Sign Up to like & getrecommendations! Published in 2017 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-017-0199-7
Abstract: Ethyl carbamate is naturally occurring compound, commonly found in many fermented foods and alcoholic beverages. During the process of plum wine production, ethyl carbamate can be formed. To this date, limited studies were conducted to… read more here.
Keywords: plum wine; carbamate; ethyl carbamate; carbamate plum ... See more keywords
Surface modification of nanocellulose through carbamate link for a selective release of chemotherapeutics
Sign Up to like & getrecommendations! Published in 2020 at "Cellulose"
DOI: 10.1007/s10570-020-03390-5
Abstract: Herein we report the synthesis of cellulose nanocrystals covalently bound to a model chemotherapeutic drug (DOXO) via a novel spacer arm, which acts both as linker and as selective releasing agent. The carbamate linkage present… read more here.
Keywords: link selective; carbamate link; modification nanocellulose; surface modification ... See more keywords
Effects of macromolecular diol containing different carbamate content on the micro-phase separation of waterborne polyurethane
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Materials Science"
DOI: 10.1007/s10853-017-1908-6
Abstract: Macromolecular diols with different carbamate content were synthesized by alterative n(PPG)/n(HMDI) ratio. The molecular weights of these macromolecular diols were measured by GPC. In addition, based on these macromolecular diols, waterborne polyurethanes (WPU) were prepared… read more here.
Keywords: phase separation; carbamate; micro phase;
Low-viscosity and efficient regeneration of carbon dioxide capture using a biphasic solvent regulated by 2-amino-2-methyl-1-propanol
Sign Up to like & getrecommendations! Published in 2019 at "Applied Energy"
DOI: 10.1016/j.apenergy.2018.10.118
Abstract: Abstract Biphasic solvents have attracted increasing attention in recent years due to their great potential to reduce the energy consumption of carbon dioxide (CO2) capture. In the present work, 2-amino-2-methyl-1-propanol (AMP) was used as a… read more here.
Keywords: biphasic solvent; viscosity; amp; carbamate ... See more keywords
Synergists action of piperonyl butoxide and S,S,S-tributyl phosphorotrithioate on toxicity of carbamate insecticides against Blattella germanica.
Sign Up to like & getrecommendations! Published in 2017 at "Asian Pacific journal of tropical medicine"
DOI: 10.1016/j.apjtm.2017.09.010
Abstract: OBJECTIVE To determine the synergists action of piperonyl butoxide (PBO) and S,S,S-tributyl phosphorotrithioate (DEF) on toxicity of carbamate insecticides against Blattella germanica in Tehran city. METHODS In the current study, German cockroach strains were collected… read more here.
Keywords: piperonyl butoxide; action piperonyl; synergists action; resistance ... See more keywords
Synthesis, molecular docking and molecular dynamics studies of novel tacrine-carbamate derivatives as potent cholinesterase inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105225
Abstract: In the present study, new tacrine derivatives containing carbamate group were synthesized and their acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition activities were evaluated. All synthesized compounds inhibited both cholinesterases at nanomolar level. Among them, ((1,2,3,4-tetrahydroacridin-9-yl)amino)ethyl(3-nitrophenyl)… read more here.
Keywords: synthesized compounds; buche; carbamate derivatives; carbamate ... See more keywords
Solid-liquid equilibrium for proteins in solutions with an unconventional salt (ammonium carbamate): Phase behavior analysis
Sign Up to like & getrecommendations! Published in 2017 at "Fluid Phase Equilibria"
DOI: 10.1016/j.fluid.2017.03.031
Abstract: Abstract In this manuscript, we report the precipitation and crystallization of three proteins (chicken egg-white lysozyme, porcine insulin and bovine insulin) using ammonium carbamate as salting-out agent. For these proteins, data on solubility, metastability limits,… read more here.
Keywords: phase; salt; crystallization; ammonium carbamate ... See more keywords
Carbamate as an accelerating group in intermolecular Pauson-Khand reaction
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2020.151974
Abstract: Abstract The Pauson-Khand reaction (PKR) is a powerful means for the construction of cyclopentenones. However, its applications have been limited to the intramolecular version of this reaction because poor yield and regioselectivity are often the… read more here.
Keywords: khand reaction; reaction; pauson khand; carbamate ... See more keywords
Stability, Reduction, and Cytotoxicity of Platinum(IV) Anticancer Prodrugs Bearing Carbamate Axial Ligands: Comparison with Their Carboxylate Analogues.
Sign Up to like & getrecommendations! Published in 2020 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.0c01541
Abstract: Platinum(IV) complexes containing carboxylate and carbamate ligands at the axial position have been reported previously. A better understanding of the similarity and difference between the two types of ligands will provide us with new insights… read more here.
Keywords: anticancer prodrugs; carboxylate; stability; carbamate axial ... See more keywords