A Nucleophilic Deprotection of Carbamate Mediated by 2-Mercaptoethanol.
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DOI: 10.1021/acs.orglett.2c01410
Abstract: Carbamates, typically used for the protection of amines, including Cbz, Alloc, and methyl carbamate, can be readily deprotected by treatment with 2-mercaptoethanol in the presence of potassium phosphate tribasic in N,N-dimethylacetamide at 75 °C. This… read more here.
Keywords: mediated mercaptoethanol; nucleophilic deprotection; carbamate mediated; deprotection ... See more keywords