Antiseizure Medication Concentrations During Pregnancy: Results From the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) Study.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2021.5487
Abstract: Importance During pregnancy in women with epilepsy, lower blood concentrations of antiseizure medications can have adverse clinical consequences. Objective To characterize pregnancy-associated concentration changes for several antiseizure medications among women with epilepsy. Design, Setting, and… read more here.
Keywords: control participants; pregnant women; dose normalized; pregnancy ... See more keywords
Carbamazepine efficacy in a severe electro‐clinical presentation of SLC13A5 ‐epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51581
Abstract: Recessive mutations in the SLC13A5 gene encoding the sodium‐dependent citrate transporter are a recently identified cause of developmental and epileptic encephalopathy. Here, we describe a child harboring a novel homozygous loss‐of‐function mutation in the SLC13A5… read more here.
Keywords: carbamazepine efficacy; severe electro; presentation; efficacy severe ... See more keywords
Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.1072
Abstract: Rifampin demonstrated dose‐dependent relative induction between cytochrome P (CYP)3A and P‐glycoprotein (P‐gp), organic anion transporting polypeptides (OATPs), or CYP2C9; P‐gp, OATP, and CYP2C9 induction was one drug–drug interaction (DDI) category lower than that observed for… read more here.
Keywords: rifabutin carbamazepine; carbamazepine; exposure; drug ... See more keywords
Long‐term treatment with carbamazepine restores cognitive abilities in a mouse model of KCNQ2 developmental and epileptic encephalopathy
Sign Up to like & getrecommendations! Published in 2025 at "Epilepsia Open"
DOI: 10.1002/epi4.70087
Abstract: Carbamazepine is the first line treatment for patients affected by KCNQ2 developmental and epileptic encephalopathy. It is efficient to reduce or stop seizures in this context. However, its effect on the neurodevelopmental outcomes is debated.… read more here.
Keywords: epileptic encephalopathy; carbamazepine; kcnq2 developmental; developmental epileptic ... See more keywords
External quality assessment for laboratory testing of HLA‐B*15:02 allele in relation to carbamazepine therapy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22242
Abstract: Due to the significant risk of developing Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), the use of carbamazepine is not recommended in patients carrying the human leukocyte antigen B (HLA‐B) *15:02 allele. In an… read more here.
Keywords: carbamazepine; quality assessment; hla allele; external quality ... See more keywords
Impact of carbamazepine on SMARCA4 (BRG1) expression in colorectal cancer: modulation by KRAS mutation status
Sign Up to like & getrecommendations! Published in 2024 at "Investigational New Drugs"
DOI: 10.1007/s10637-024-01418-2
Abstract: SMARCA4 is a gene traditionally considered a tumor suppressor. Recent research has however found that SMARCA4 likely promotes cancer growth and is a good target for cancer treatment. The drug carbamazepine, an autophagy inducer, was… read more here.
Keywords: colorectal cancer; mutation status; cancer; carbamazepine ... See more keywords
Clinical Features, Intensive Care Needs, and Outcome of Carbamazepine Poisoning in Children
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Pediatrics"
DOI: 10.1007/s12098-022-04155-7
Abstract: Carbamazepine is commonly used antiseizure medication with a narrow therapeutic range. The data on carbamazepine poisoning in children from India is limited. In this retrospective study, the authors reported 10 children with carbamazepine poisoning admitted… read more here.
Keywords: carbamazepine poisoning; carbamazepine; intensive care; clinical features ... See more keywords
Phenotypical and molecular changes induced by carbamazepine and propranolol on larval stages of Mytilus galloprovincialis.
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.06.045
Abstract: The possible impact of carbamazepine (CBZ) and propranolol (PROP), two widespread pharmaceuticals in the aquatic environment, were investigated on morphology and gene transcription of early larvae of Mytilus galloprovincialis. Pharmaceuticals were first tested in a… read more here.
Keywords: phenotypical molecular; changes induced; prop; carbamazepine ... See more keywords
The relationship between cyto-genotoxic damage and oxidative stress produced by emerging pollutants on a bioindicator organism (Allium cepa): The carbamazepine case.
Sign Up to like & getrecommendations! Published in 2020 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.126675
Abstract: The carbamazepine (CBZ) is one of the most frequently detected anticonvulsant drugs in water bodies. Although there are reports of its ecotoxicological effects in the scientific literature, toxicity studies have not focused on establishing the… read more here.
Keywords: allium cepa; carbamazepine; stress produced; stress ... See more keywords
An integrated metabolomics and proteogenomics approach reveals molecular alterations following carbamazepine exposure in the male mussel Mytilus galloprovincialis.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.131793
Abstract: Carbamazepine is one of the most abundant pharmaceutical active compounds detected in aquatic systems. Based on laboratory exposures, carbamazepine has been proven to adversely affect aquatic organisms. However, the underlying molecular events remain poorly understood.… read more here.
Keywords: mytilus galloprovincialis; carbamazepine; integrated metabolomics; proteogenomics approach ... See more keywords
Insights into the wavelength-dependent photolysis of chlorite: Elimination of carbamazepine and formation of chlorate.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.132505
Abstract: Simultaneous removal of chlorite (ClO2-) and organic micro-pollutants (OMPs) by the irradiation of UV is a novel process. In this study we used UV light emitting diode (UV-LED) as a new UV source to systematically… read more here.
Keywords: carbamazepine; removal; chlorite; clo2 ... See more keywords