In vitro evaluation of double‐carbapenem combinations against OXA‐48‐producing Klebsiella pneumoniae isolates using time‐kill studies
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DOI: 10.1099/jmm.0.000725
Abstract: Purpose. The aim of this study was to evaluate the in vitro activity of double‐carbapenem combinations against OXA‐48‐producing Klebsiella pneumoniae clinical isolates. Methodology. Double combinations of ertapenem, meropenem and imipenem were evaluated for synergy and… read more here.
Keywords: imipenem; methodology; double carbapenem; carbapenem combinations ... See more keywords
Carbapenem Combinations for Infections Caused by Carbapenemase-Producing Pseudomonas aeruginosa: Experimental In Vitro and In Vivo Analysis
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DOI: 10.3390/antibiotics11091212
Abstract: In the context of difficult-to-treat carbapenem-resistant Pseudomonas aeruginosa infections, we evaluated imipenem, meropenem, and doripenem combinations against eleven carbapenemase-producing P. aeruginosa isolates. According to the widespread global distribution of high-risk clones and carbapenemases, four representative… read more here.
Keywords: plus meropenem; carbapenem combinations; pseudomonas aeruginosa; doripenem ... See more keywords