Non-intravenous carbapenem-sparing antibiotics for the definitive treatment of bacteremia due to Enterobacteriaceae-producing ESBL or AmpC β-lactamase. A propensity score study.
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DOI: 10.1016/j.ijantimicag.2019.05.004
Abstract: BACKGROUND Carbapenems are considered the treatment of choice for extended-spectrum β-lactamase (ESBL) or AmpC β-lactamase-producing Enterobacteriaceae bacteremia. Data on the effectiveness of non-intravenous carbapenem-sparing antibiotic options are limited. OBJECTIVE To compare the 30 day-mortality and… read more here.
Keywords: treatment; bacteremia; esbl ampc; carbapenem sparing ... See more keywords
Carbapenem sparing in the management of post‐transrectal prostate biopsy bacteraemia
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DOI: 10.1111/ans.15322
Abstract: Sepsis following transrectal ultrasound (TRUS)‐guided prostate biopsy is a major complication. With the emergence of multidrug‐resistant organisms, empirical use of carbapenem antibiotics has been increasing. This study, conducted in the Illawarra Shoalhaven Local Health District… read more here.
Keywords: prostate; carbapenem sparing; sparing management; prostate biopsy ... See more keywords
Clinical syndromes and treatment location predict utility of carbapenem sparing therapies in ceftriaxone-non-susceptibleEscherichia colibloodstream infection
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DOI: 10.1186/s12941-020-00400-z
Abstract: Background Cefiderocol, ceftazidime-avibactam, ceftolozane-tazobactam, intravenous fosfomycin and plazomicin represent potential carbapenem sparing agents for extended-spectrum-beta-lactamase or AmpC beta-lactamase producing Escherichia coli infection. However, available data is limited in predicting the volume of carbapenem therapy which… read more here.
Keywords: 100 patient; carbapenem sparing; infection; patient days ... See more keywords
Evaluation of Carbapenem Use Before and After Implementation of an Antimicrobial Stewardship-Led Carbapenem-Sparing Strategy in a Lebanese Tertiary Hospital: A Retrospective Study
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DOI: 10.3389/fcimb.2022.729491
Abstract: Purpose The use of carbapenem before and after implementation of an antimicrobial stewardship-led carbapenem-sparing strategy at a tertiary care center in Lebanon was evaluated. Methods A retrospective, observational chart review was performed on all hospitalized… read more here.
Keywords: antimicrobial stewardship; sparing strategy; carbapenem sparing; carbapenem ... See more keywords
Carbapenem-Sparing Strategies for ESBL Producers: When and How
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DOI: 10.3390/antibiotics9020061
Abstract: Extended spectrum β-lactamase (ESBL)-producing bacteria are prevalent worldwide and correlated with hospital infections, but they have been evolving as an increasing cause of community acquired infections. The spread of ESBL constitutes a major threat for… read more here.
Keywords: strategies esbl; esbl producers; sparing strategies; carbapenem sparing ... See more keywords