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Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.02.063
Abstract: Abstract An efficient synthesis of new six-membered carbasugars in both L-form and D-form starting from N–acetylglucosamine is described. The key synthetic steps involved regioselective protection and deprotection, Ferrier carbocyclization, Peterson olefination, hydroboration and stereoselective epoxidation…
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Keywords:
design synthesis;
synthesis acetylglucosamine;
synthesis;
derived carbasugar ... See more keywords
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Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b00945
Abstract: A convergent synthesis of 5a-carbasugar analogues of the n-Pr-variant of SL0101 is described. The analogues were synthesized in an effort to find compounds with potent in vivo efficacy in the inhibition of p90 ribosomal s6…
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Keywords:
stereoselective synthesis;
carbasugar analogues;
synthesis evaluation;
evaluation substituted ... See more keywords