The anticancer activity of carbazole alkaloids.
Sign Up to like & getrecommendations! Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202100277
Abstract: Chemotherapy is the first choice for the majority of cancers, but severe side effects and drug resistance restrict the actual clinical efficacy. Carbazole alkaloids, mainly from the Rutaceae family, possess favorable donor ability, good planarity,… read more here.
Keywords: anticancer; carbazole alkaloids; activity carbazole; anticancer activity ... See more keywords
Carbazole alkaloids from the fruits of Clausena anisum-olens with potential PTP1B and α-glucosidase inhibitory activities.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104775
Abstract: The phytochemical investigation on the fruits of Clausena anisum-olens led to the isolation of 18 carbazole alkaloids (1-18), containing three new ones, clausenanisines A-C (1-3), and three new naturally occurring carbazole alkaloids, clausenanisines D-F (4-6),… read more here.
Keywords: inhibitory activities; ptp1b glucosidase; anisum olens; carbazole alkaloids ... See more keywords
Total synthesis of carbazole alkaloids
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.01.003
Abstract: Abstract A Suzuki-Miyaura cross coupling, followed by triphenylphosphine mediated Cadogan reductive cyclization sequence provided efficient access to a series of carbazole alkaloids. In the present work, this approach was applied to the total synthesis of… read more here.
Keywords: carbazole; carbazole alkaloids; synthesis carbazole; methoxy carbazole ... See more keywords
Carbazole Alkaloids with Potential Neuroprotective Activities from the Fruits of Clausena lansium.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b00961
Abstract: Clausena lansium, also known as wampee, is a species of strongly scented evergreen trees belonging to the genus Clausena (Rutaceae), which is native to southern China. Its ripe fruits have been consumed as a very… read more here.
Keywords: neuroprotective effects; clausena lansium; fruits lansium; lansium ... See more keywords
Carbazole alkaloids from Clausena emarginata with their potential antiproliferative activities
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DOI: 10.1080/14786419.2018.1475386
Abstract: Abstract A phytochemical investigation on the stems and leaves of Clausena emarginata led to the isolation of a previously undescribed carbazole alkaloid, clausemargine A (1), together with 11 known analogues (2–12). The structure of 1… read more here.
Keywords: emarginata potential; clausena emarginata; alkaloids clausena; antiproliferative activities ... See more keywords
Production of carbazole alkaloids through callus and suspension cultures in Clausena harmandiana
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DOI: 10.1080/14786419.2018.1533833
Abstract: Abstract Carbazole alkaloids are major constituents in Clausena spp. and exhibit a wide range of biological activities. The roots of Clausena harmandiana are a rich source of active carbazole alkaloids. However, its roots take several… read more here.
Keywords: callus suspension; alkaloids callus; carbazole; clausena harmandiana ... See more keywords
Phyto-Carbazole Alkaloids from the Rutaceae Family as Potential Protective Agents against Neurodegenerative Diseases
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DOI: 10.3390/antiox11030493
Abstract: Plant-derived (phyto) carbazole alkaloids are an important class of compounds, presented in the family of Rutaceae (Genera Murraya, Clausena, Glycosmis, Micromelum and Zanthoxylum). Due to several significant biological activities, such as antitumor, antibacterial, antiviral, antidiabetic,… read more here.
Keywords: phyto carbazole; family; agents neurodegenerative; carbazole alkaloids ... See more keywords