Synthesis and structure-activity relationship study of water-soluble carbazole sulfonamide derivatives as new anticancer agents.
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DOI: 10.1016/j.ejmech.2020.112181
Abstract: Here, we formulated and investigated the structure-activity relationships of novel N-substituted carbazole sulfonamide derivatives with improved physicochemical properties. Most of these new compounds displayed good aqueous solubility. Certain molecules presented strong in vitro antiproliferative and in vivo… read more here.
Keywords: sulfonamide derivatives; structure activity; water soluble; carbazole sulfonamide ... See more keywords