Implications for an imidazol-2-yl carbene intermediate in the rhodanase-catalyzed C-S bond formation reaction of anaerobic ergothioneine biosynthesis.
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DOI: 10.1021/acscatal.0c04886
Abstract: In the anaerobic ergothioneine biosynthetic pathway, a rhodanese domain containing enzyme (EanB) activates tne hercynine's sp2 ε-C-H Dona ana replaces it with a C-S bond to produce ergothioneine. The key intermediate for this trans-sulfuration reaction… read more here.
Keywords: anaerobic ergothioneine; carbene intermediate; eanb; reaction ... See more keywords