Synthesis of α-Ketoamides via Gold(I) Carbene Intermediates.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01489
Abstract: α-Ketoamides have been found to be an important functional group in a broad spectrum of inhibitors such as the Corona virus and other viruses. Here we report an unprecedented gold-catalyzed 2-fold reaction of a bromoalkyne… read more here.
Keywords: carbene intermediates; synthesis ketoamides; ketoamides via; gold carbene ... See more keywords
Dichotomy of platinum(II) and gold(III) carbene intermediates switching from N- to O-selectivity.
Sign Up to like & getrecommendations! Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29326-0
Abstract: Pt(II) and Au(III)-mediated intermolecular divergent annulations of benzofurazans and ynamides highlighted the N- to O-selectivity of tunable metal carbene intermediates. PtCl2 with a bulky phosphite ligand resulted in the specific synthesis of six-membered quinoxaline N-oxides… read more here.
Keywords: gold iii; gold; iii; carbene intermediates ... See more keywords