Organic solvent stability and long‐term storage of myoglobin‐based carbene transfer biocatalysts
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1972
Abstract: Recent years have witnessed a rapid increase in the application of enzymes for chemical synthesis and manufacturing, including the industrial‐scale synthesis of pharmaceuticals using multienzyme processes. From an operational standpoint, these bioprocesses often require robust… read more here.
Keywords: carbene transfer; carbene; myoglobin based; stability ... See more keywords
Enabling Cyclopropanation Reactions of Imidazole Heterocycles via Chemoselective Photochemical Carbene Transfer Reactions of NHC-Boranes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00609
Abstract: Herein we report a site-selective cyclopropanation of N-heterocyclic carbene (NHC)-borane complexes via photochemical carbene transfer reactions. By subtle changes to the reaction conditions, this approach can be further extended toward the difunctionalization of NHC-boranes via… read more here.
Keywords: carbene transfer; transfer reactions; photochemical carbene; cyclopropanation ... See more keywords
Photochemical Carbene-Transfer Reaction of Vinyldiazo Compounds: Synthesis of 1-Pyrrolines via Methylenation/[2+3] Annulation.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c04229
Abstract: Herein, we report a new class of vinyldiazo compounds called bromo-diazoenals that effectively suppress the inherent 2π-electrocyclization typically observed in vinyldiazo compounds under photochemical conditions. Upon irradiation with visible light, these Br-diazoenal compounds generate singlet… read more here.
Keywords: annulation; vinyldiazo compounds; carbene transfer; carbene ... See more keywords
Bridging and axial carbene binding modes in cobalt corrole complexes: effect on carbene transfer.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc07073d
Abstract: Catalytically relevant intermediates in carbene transfer reactions from a diazo precursor were investigated using cobalt corrole complexes. Two divergent mechanisms are proposed depending on the oxidation state of the cobalt center. Mechanistically driven factors for… read more here.
Keywords: cobalt corrole; carbene transfer; carbene; corrole complexes ... See more keywords
Iron catalysts with N-ligands for carbene transfer of diazo reagents.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Society reviews"
DOI: 10.1039/d0cs00221f
Abstract: Transition-metal-catalyzed carbene transfer reactions, involving diazo compounds and their precursors, are powerful tools for creating new C-C bonds. Depending on the involved catalytic system, the carbene insertion can efficiently be driven towards a specific functional… read more here.
Keywords: iron catalysts; carbene transfer; diazo; catalysts ligands ... See more keywords
Highly electrophilic silver carbenes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04845k
Abstract: Catalytic carbene transfer reactions are fundamental transformations in modern organic synthesis, which enable direct access to diverse structurally complex molecules. Despite diazo precursors playing a crucial role in catalytic carbene transfer reactions, most reported methodologies… read more here.
Keywords: carbene transfer; silver carbenes; silver; highly electrophilic ... See more keywords
Graphene oxide catalysed carbene transfer reaction in water: A highly green and selective approach to access 3,3’,3’’-trisindoles
Sign Up to like & getrecommendations! Published in 2024 at "Green Chemistry"
DOI: 10.1039/d3gc03966h
Abstract: The insertion or transfer of carbene using diazo compounds as a precursor is being used widely to synthesize/functionalize different classes of organic compounds. While different types of catalysts like transition... read more here.
Keywords: oxide catalysed; graphene oxide; carbene transfer; catalysed carbene ... See more keywords
Photoinduced carbene transfer for copper-catalyzed asymmetric [4+1] cycloadditions: an entry to chiral indolines bearing quaternary stereocenters
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00551h
Abstract: Indoline skeletons are widely found in many natural isolates and pharmaceuticals, making indoline synthesis an ongoing research hotspot in synthetic chemistry. However, the catalytic asymmetric de novo construction of indolines... read more here.
Keywords: carbene transfer; chemistry; catalyzed asymmetric; transfer copper ... See more keywords