Synthesis of 2-aminothiazoles via rhodium-catalyzed carbenoid insertion/annulation of sulfoxonium ylides with thioureas
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.02.052
Abstract: Abstract Sulfoxonium ylides as carbene precursors couple smoothly with thioureas in the presence of 5 mol% of rhodium(II) acetate dimmer via carbenoid insertion to afford the corresponding 2-aminothiazoles with high chemoselectivity, providing a facile and efficient… read more here.
Keywords: sulfoxonium ylides; synthesis aminothiazoles; carbenoid insertion; rhodium ... See more keywords
Rh(iii)-catalyzed regioselective intermolecular N-methylene Csp3–H bond carbenoid insertion† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc03802j
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c7sc03802j
Abstract: A Rh(iii)-catalyzed regioselective intermolecular carbenoid insertion into the N-methylene Csp3–H bond has been achieved via an outer-sphere pathway. read more here.
Keywords: methylene csp3; regioselective intermolecular; iii catalyzed; csp3 bond ... See more keywords
Iron-Catalyzed Carbenoid Insertion into C(sp3)–H Bonds
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DOI: 10.1055/s-0036-1588743
Abstract: An iron-catalyzed carbenoid insertion into C–H bonds of alkanes was developed with high activity (turnover numbers up to 690 in a gram-scale experiment) and chemoselectivity. This non-heme iron-catalyzed C(sp3)–H insertion reaction provides an efficient strategy… read more here.
Keywords: insertion; iron catalyzed; catalyzed carbenoid; sp3 bonds ... See more keywords