Peptides, Peptidomimetics, and Carbohydrate-Peptide Conjugates as Amyloidogenic Aggregation Inhibitors for Alzheimer's Disease.
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DOI: 10.1021/acschemneuro.8b00185
Abstract: Alzheimer's disease (AD) is a progressive neurodegenerative disorder accounting for 60-80% of dementia cases. For many years, AD causality was attributed to amyloid-β (Aβ) aggregated species. Recently, multiple therapies that target Aβ aggregation have failed… read more here.
Keywords: aggregation; alzheimer disease; peptides peptidomimetics; carbohydrate peptide ... See more keywords