Articles with "carboline acylhydrazone" as a keyword



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Discovery of novel β-carboline/acylhydrazone hybrids as potent antitumor agents and overcome drug resistance.

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Published in 2018 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2018.05.003

Abstract: Twenty-four novel β-carboline/acylhydrazone hybrids were synthesized and evaluated for their in vitro antiproliferative activity. Among them, 12r exhibited the most potent activity, with IC50 values of 1-2 μM against panel of cancer cell lines and retained significant… read more here.

Keywords: novel carboline; acylhydrazone hybrids; discovery novel; carboline acylhydrazone ... See more keywords