Bioactivity-guided isolation of β-Carboline alkaloids with potential anti-hepatoma effect from Picrasma quassioides (D. Don) Benn.
Sign Up to like & getrecommendations! Published in 2018 at "Fitoterapia"
DOI: 10.1016/j.fitote.2018.08.004
Abstract: β-Carboline alkaloids in Picrasma quassioides (D. Don) Benn. have been proven to possess inhibitory activity against various cancer cells. However, their effect on hepatocellular carcinoma and structure-activity relationships (SAR) have not been systematically reported. In… read more here.
Keywords: picrasma quassioides; bioactivity; quassioides benn; effect ... See more keywords
A new cinnamamide derivative and two new β-carboline alkaloids from the stems of Picrasma quassioides.
Sign Up to like & getrecommendations! Published in 2019 at "Fitoterapia"
DOI: 10.1016/j.fitote.2019.104375
Abstract: Picrasamide A (1), a new cinnamamide derivative, together with two new β-carboline alkaloids (2 and 3) and five known β-carboline alkaloids (4-8) were isolated from the stems of Picrasma quassioides (D. Don) Benn. Their structures… read more here.
Keywords: new cinnamamide; two new; cinnamamide derivative; carboline alkaloids ... See more keywords
β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial-mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.112096
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The plant Arenaria kansuensis is used in traditional medicine to treat lung inflammation for a long time. However, the anti-pulmonary fibrosis effect and its corresponding bioactive constituents of this plant have not been… read more here.
Keywords: fibrosis; effect; pulmonary fibrosis; part1 ... See more keywords
Isolation and structure elucidation of siliendines A‒D, new β-carboline alkaloids from Silene seoulensis
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2020.01.010
Abstract: Abstract Four new β-carboline alkaloids, siliendines A–D (1‒4), and four known metabolites (5–8) were isolated from the ethanolic extract of the aerial parts of Silene seoulensis using various chromatographic methods. The structures of the new… read more here.
Keywords: structure elucidation; silene seoulensis; new carboline; carboline alkaloids ... See more keywords
Orthoscuticellines A-E, β-Carboline Alkaloids from the Bryozoan Orthoscuticella ventricosa Collected in Australia.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.9b00933
Abstract: Antiplasmodial high-throughput screening of extracts derived from marine invertebrates collected from northern NSW, Australia, resulted in the methanol extract of the bryozoan Orthoscuticella ventricosa being identified as inhibitory toward the 3D7 strain of Plasmodium falciparum.… read more here.
Keywords: carboline alkaloids; bryozoan orthoscuticella; carboline; orthoscuticella ventricosa ... See more keywords
Investigation of Ayahuasca β-Carboline Alkaloids and Tryptamine in Sweat Samples from Religious Community Participants by GC-MS.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkz116
Abstract: Ayahuasca, a hallucinogenic beverage used in religious rituals in South America, has become a global phenomenon. Its main active components are the β-carbolines alkaloids, harmine (HRM) and harmaline (HRL), as well as the potent hallucinogen… read more here.
Keywords: carboline alkaloids; sweat; investigation ayahuasca; investigation ... See more keywords
Simple naturally occurring β-carboline alkaloids – role in sustainable theranostics
Sign Up to like & getrecommendations! Published in 2022 at "Physical Sciences Reviews"
DOI: 10.1515/psr-2022-0132
Abstract: Abstract This review is a brief treatise on some simple β-carboline alkaloids that are abundantly available in plants, animals and foodstuff. These alkaloids are well known for their pharmacological action as well as their allelopathic… read more here.
Keywords: simple naturally; carboline alkaloids; sustainable theranostics; alkaloids role ... See more keywords
β-Carboline Alkaloids in Soy Sauce and Inhibition of Monoamine Oxidase (MAO)
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28062723
Abstract: Monoamine oxidase (MAO) oxidizes neurotransmitters and xenobiotic amines, including vasopressor and neurotoxic amines such as the MPTP neurotoxin. Its inhibitors are useful as antidepressants and neuroprotectants. This work shows that diluted soy sauce (1/3) and… read more here.
Keywords: mao; carboline alkaloids; monoamine oxidase; oxidase mao ... See more keywords
Lethal and Sublethal Toxicity of Beta-Carboline Alkaloids from Peganum harmala (L.) against Aedes albopictus Larvae (Diptera: Culicidae)
Sign Up to like & getrecommendations! Published in 2023 at "Toxics"
DOI: 10.3390/toxics11040341
Abstract: Plant-derived agents are powerful bio-pesticides for the eco-friendly control of mosquito vectors and other blood-sucking arthropods. The larval toxicity of beta-carboline alkaloids against the Asian tiger mosquito, Aedes albopictus (Skuse) (Diptera: Culicidae), was investigated under… read more here.
Keywords: carboline alkaloids; beta carboline; instar larvae; toxicity ... See more keywords