Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors.
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DOI: 10.1016/j.ejmech.2017.12.055
Abstract: A series of new podophyllotoxin linked β-carboline congeners have been synthesized by coupling various substituted β-carboline acids with 4β-aminopodophyllotoxin. Evaluation of their anticancer activity against a panel of human cancer cell lines such as lung… read more here.
Keywords: topoisomerase inhibitors; linked carboline; topoisomerase; cancer ... See more keywords