Calculating dose‐averaged linear energy transfer in an analytical treatment planning system for carbon‐ion radiotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13866
Abstract: Abstract Background Compelling evidence shows the association between the relative biological effectiveness (RBE) of carbon‐ion radiotherapy (CIRT) and the dose averaged linear energy transfer (LETd). However, the ability to calculate the LETd in commercially available… read more here.
Keywords: carbon ion; treatment planning; energy; ion radiotherapy ... See more keywords
A multi‐institutional retrospective study of carbon‐ion radiotherapy for non‐squamous cell malignant tumors of the nasopharynx: Subanalysis of Japan Carbon‐Ion Radiation Oncology Study Group study 1402 HN
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DOI: 10.1002/cam4.1884
Abstract: This multi‐institutional retrospective study focused on the clinical outcome of carbon‐ion radiotherapy (C‐ion RT) for non‐squamous cell malignant tumors of the nasopharynx. read more here.
Keywords: multi institutional; carbon ion; oncology; study ... See more keywords
Dose–volume constraints for head‐and‐neck cancer in carbon ion radiotherapy: A literature review
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DOI: 10.1002/cam4.5641
Abstract: Carbon ion radiotherapy (CIRT) has been applied in cancer treatment for over 25 years. However, guidelines for dose–volume constraints have not been established yet. The aim of this review is to summarize the dose–volume constraints in… read more here.
Keywords: carbon ion; dose volume; volume constraints; ion radiotherapy ... See more keywords
Mitochondrial proteomics reveals the mechanism of spermatogenic cells apoptosis induced by carbon ion radiation in zebrafish
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DOI: 10.1002/jcp.28808
Abstract: The mitochondrial proteins involved in spermatogenic cells apoptosis in zebrafish after carbon ion radiation (CIR) were screened. The relative biological effectiveness (RBE) of CIR in zebrafish testes was investigated. Apoptosis of testicular cells was measured… read more here.
Keywords: mitochondrial proteins; cir; spermatogenic cells; apoptosis ... See more keywords
Diffusion‐weighted MRI treatment monitoring of primary hypofractionated proton and carbon ion prostate cancer irradiation using raster scan technique
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.25635
Abstract: To investigate parametric changes in the apparent diffusion coefficient (ADC) at multiple timepoints during and after completion of primary proton and carbon ion irradiation of prostate cancer (PCa) as compared with normal‐appearing prostate parenchyma. read more here.
Keywords: carbon ion; proton carbon; diffusion; prostate cancer ... See more keywords
Application of variance‐based uncertainty and sensitivity analysis to biological modeling in carbon ion treatment plans
Sign Up to like & getrecommendations! Published in 2019 at "Medical Physics"
DOI: 10.1002/mp.13306
Abstract: PURPOSE In ion beam therapy, biological models to estimate the relative biological effectiveness (RBE) and subsequently the RBE-weighted dose (RWD) are needed in treatment planning and plan evaluation. The required biological parameters as well as… read more here.
Keywords: uncertainty; carbon ion; treatment; variance based ... See more keywords
Validation of a model for physical dose variations in irregularly moving targets treated with carbon ion beams.
Sign Up to like & getrecommendations! Published in 2019 at "Medical physics"
DOI: 10.1002/mp.13662
Abstract: PURPOSE In particle therapy, conventional treatment planning systems rely on an imaging representation of the irradiated region to compute the dose. For irregular breathing, when an imaging dataset describing the actual motion is not available,… read more here.
Keywords: carbon ion; motion; physical dose;
Dosimetric Evaluation of 4D-CBCT Reconstructed by Simultaneous Motion Estimation and Image Reconstruction (SMEIR) for Carbon Ion Therapy of Lung Cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Medical physics"
DOI: 10.1002/mp.13706
Abstract: PURPOSE Motion management is critical for the efficacy of carbon ion therapy for moving targets such as lung tumors. We evaluated the feasibility of using 4D-CBCT reconstructed by Simultaneous Motion Estimation and Image Reconstruction (SMEIR)… read more here.
Keywords: carbon ion; motion; ion therapy; carbon ... See more keywords
Technical note: Impact of beamline‐specific particle energy spectra on clinical plans in carbon ion beam therapy
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DOI: 10.1002/mp.15652
Abstract: Abstract Purpose The Local Effect Model version one (LEM I) is applied clinically across Europe to quantify the relative biological effectiveness (RBE) of carbon ion beams. It requires the full particle fluence spectrum differential in… read more here.
Keywords: beamline; carbon ion; beam; energy ... See more keywords
Radio-fluorogenic nanoclay gel dosimeters with reduced linear energy transfer dependence for carbon-ion beam radiotherapy.
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DOI: 10.1002/mp.16092
Abstract: PURPOSE The precise assessment of the dose distribution of high linear energy transfer (LET) radiation remains a challenge, since the signal of most dosimeters will be saturated due to the high ionization density. Such measurements… read more here.
Keywords: gel; carbon ion; ion; ion beam ... See more keywords
Technical note: A method to evaluate the effect of scanning beam delivery error on 3D dose and its utilization on carbon ion radiotherapy for prostate cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.16109
Abstract: PURPOSE To establish a method for evaluating the effect of scanning ion beam delivery error on three-dimensional (3D) dose reconstructed on patients' CT based on log file. MATERIALS AND METHODS This study used the MATLAB… read more here.
Keywords: carbon ion; prostate cancer; treatment; delivery ... See more keywords