Beetleane A and Epicoane A: Two Carbon Skeletons Produced by Epicoccum nigrum.
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DOI: 10.1021/acs.orglett.1c00731
Abstract: Two novel natural products, beetleane A (1) and epicoane A (2), were obtained from the metabolites of an endophytic Epicoccum nigrum. Compound 1 has a unique beetlelike structure that is constructed by the fusion and… read more here.
Keywords: skeletons produced; epicoccum nigrum; two carbon; carbon skeletons ... See more keywords
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor.
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DOI: 10.1021/acs.orglett.7b01813
Abstract: Euphordraculoates A (1) and B (2), featuring tigliane diterpenoids with two new carbon skeletons, were characterized as metabolites of Euphorbia dracunculoides and semisynthetic products, respectively. Their structures were determined by spectroscopic analyses and X-ray crystallography.… read more here.
Keywords: tigliane diterpenoids; new carbon; carbon skeletons; euphorbia dracunculoides ... See more keywords
Novel carbon skeletons activate human NicotinAMide Phosphoribosyl Transferase (NAMPT) enzyme in biochemical assay
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DOI: 10.1371/journal.pone.0283428
Abstract: Nicotinamide adenine dinucleotide (NAD) is a central molecule in cellular metabolism that has been implicated in human health, the aging process, and an array of human diseases. NAD is well known as an electron storage… read more here.
Keywords: carbon skeletons; carbon; novel carbon; nampt enzyme ... See more keywords