Computational study on the NHC-catalyzed synthesis of 2,3-disubstituted indoles: mechanism, key intermediate and the role of the catalyst
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DOI: 10.1039/c8qo00139a
Abstract: In this work, the possible reaction mechanisms and the role of N-heterocyclic carbene (NHC) catalysts in the umpolung reaction of imines to generate 2-substituted indole-3-acetic acid derivatives were investigated by density functional theory (DFT). Two… read more here.
Keywords: carbon; unsaturated ester; carbon unsaturated; imine carbon ... See more keywords