Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c7py01345k
Abstract: En route towards improved delivery systems for targeted chemotherapy, we propose a straightforward approach for the hydrophobic modification of the acrylamide N-(2-Hydroxyethyl)acrylamide (HEAm). An ethyl or benzyl group was introduced via a hydrolytically sensitive carbonate… read more here.
Keywords: polymerization; block; carbonate ester; heam ... See more keywords
Vanillin derived a carbonate dialdehyde and a carbonate diol: novel platform monomers for sustainable polymers synthesis
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DOI: 10.1039/c8ra07185c
Abstract: Vanillin has been regarded as one of the important biomass-based platform chemicals for aromatic polymers synthesis. Herein, novel symmetric bis(4-formyl-2-methoxyphenyl)carbonate (BFMC) and bis(4-(hydroxymethyl)-2-methoxyphenyl)carbonate (BHMC) polymeric monomers have been synthesized in high yields using vanillin as… read more here.
Keywords: poly carbonate; carbonate ester; ester oligomers; platform ... See more keywords
Orally Bioavailable Endochin-Like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts
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DOI: 10.1128/aac.00535-20
Abstract: Toxoplasmosis is a potentially fatal infection for immunocompromised people and the developing fetus. Current medicines for toxoplasmosis have high rates of adverse effects that interfere with therapeutic and prophylactic regimens. Endochin-like quinolones (ELQs) are potent… read more here.
Keywords: toxoplasmosis; toxoplasma gondii; carbonate ester; endochin like ... See more keywords