1-[(4'-Chlorophenyl) carbonyl-4-(aryl) thiosemicarbazide derivatives as potent urease inhibitors: Synthesis, in vitro and in silico studies.
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DOI: 10.1016/j.bioorg.2018.05.017
Abstract: A series of 1-[(4'-chlorophenyl)carbonyl-4-(aryl)thiosemicarbazide derivatives 1-25 was synthesized and characterized by spectroscopic techniques such as EI-MS and 1H NMR. All compounds were screened for urease inhibitory activity in vitro and demonstrated excellent inhibitory activity in… read more here.
Keywords: chlorophenyl carbonyl; thiosemicarbazide derivatives; carbonyl aryl; ic50 ... See more keywords