Pd-catalyzed carbonylative α-arylation of azlactones: A formal four-component coupling route to α,α-disubstituted amino acids
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DOI: 10.1016/j.jcat.2018.04.027
Abstract: Abstract We report on a Pd-catalyzed carbonylative α-arylation of azlactones derived from alanine, providing facile access to α,α-disubstituted amino acids after an alcoholysis step. A range of aryl iodides proved to be suitable substrates in… read more here.
Keywords: amino acids; disubstituted amino; catalyzed carbonylative; carbonylative arylation ... See more keywords