Real‐world data of atezolizumab plus carboplatin and etoposide in elderly patients with extensive‐disease small‐cell lung cancer
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DOI: 10.1002/cam4.4938
Abstract: The aim of this study was to assess the effectiveness and tolerability of atezolizumab plus carboplatin and etoposide combination chemotherapy in elderly patients with extensive‐disease (ED) small‐cell lung cancer (SCLC). read more here.
Keywords: elderly patients; carboplatin etoposide; plus carboplatin; patients extensive ... See more keywords
A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Lung cancer"
DOI: 10.1016/j.lungcan.2016.12.020
Abstract: OBJECTIVES This multicenter, open-label, randomized phase II study evaluated the efficacy and safety of LY2510924 (LY) added to first-line standard of care (SOC) chemotherapy for extensive-disease small cell lung cancer (ED-SCLC) and explored the predictive… read more here.
Keywords: phase study; randomized phase; carboplatin etoposide; lung cancer ... See more keywords
ETMR-14. TREATMENT OF EMBRYONAL TUMOURS WITH MULTILAYERED ROSETTES (ETMR) WITH CARBOPLATIN-ETOPOSIDE INDUCTION AND TANDEM HIGH-DOSE CHEMOTHERAPY WITHIN THE PROSPECTIVE HIT-TRIALS AND REGISTRIES
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.218
Abstract: Abstract BACKGROUND Embryonal tumours with multilayered rosettes (ETMR) are highly aggressive tumors, mostly occurring in infants. Published clinical data refer to retrospective cohorts of inhomogeneously treated patients. Here, we describe the outcome of patients, who… read more here.
Keywords: chemotherapy; tandem high; high dose; etoposide induction ... See more keywords
Population pharmacokinetics of carboplatin, etoposide and melphalan in children: a re‐evaluation of paediatric dosing formulas for carboplatin in patients with normal or mild impairment of renal function
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13774
Abstract: Carboplatin dosage is calculated by using the estimated glomerular filtration rate (GFR) to achieve a target plasma area under the plasma concentration–time curve (AUC). The aims of the present study were to investigate factors that… read more here.
Keywords: etoposide melphalan; melphalan children; children evaluation; population pharmacokinetics ... See more keywords
Daratumumab with ifosfamide, carboplatin and etoposide for the treatment of relapsed plasmablastic lymphoma
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DOI: 10.1111/bjh.18228
Abstract: cell neoplasms. Bortezomib, a proteasome inhibitor initially used in multiple myeloma, has been combined with chemotherapy and shown to be effective in frontline PBL. 5 In the relapsed setting, PBL treatment is even more difficult… read more here.
Keywords: daratumumab; ifosfamide carboplatin; daratumumab ifosfamide; four patients ... See more keywords
Abstract CT199: IMpower133: Primary efficacy and safety + CNS-related adverse events in a Ph1/3 study of first-line (1L) atezolizumab (atezo) + carboplatin + etoposide in extensive-stage SCLC (ES-SCLC)
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Trials"
DOI: 10.1158/1538-7445.am2019-ct199
Abstract: Background Platinum chemotherapy (carboplatin or cisplatin) + etoposide is the current 1L standard of care treatment (tx) for ES-SCLC. Despite high response rates on this regimen, patient (pt) outcomes remain poor. IMpower133 is a Ph1/3,… read more here.
Keywords: carboplatin etoposide; efficacy; atezo carboplatin; sclc ... See more keywords
Alternative treatment scheme of seminoma for carboplatin, etoposide and bleomycin (CEB)
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DOI: 10.26641/2307-5279.21.1.2017.150085
Abstract: Герміногенние пухлини яєчка високочутливі до поліхіміотерапії (ПХТ). Стандартом лікування хворих семіномой в II-III стадіях є схеми 3 РЕВ або 4 РЕ. Лікування пов'язане з гострою і відстроченої токсичністю. Проаналізовано результати лікування 17 пацієнтів за схемою… read more here.
Keywords: scheme seminoma; treatment scheme; etoposide bleomycin; seminoma carboplatin ... See more keywords
Pretreatment glasgow prognostic score predicts survival among patients administered first-line atezolizumab plus carboplatin and etoposide for small cell lung cancer
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DOI: 10.3389/fonc.2022.1080729
Abstract: Background There are no established predictive biomarkers for the effectiveness of first-line atezolizumab plus carboplatin and etoposide therapy in patients with small-cell lung cancer (SCLC). Therefore, the current study aimed to investigate whether the Glasgow… read more here.
Keywords: carboplatin etoposide; first line; plus carboplatin; line atezolizumab ... See more keywords