The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82780-6
Abstract: Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, lacking effective therapy. Many TNBCs show remarkable response to carboplatin-based chemotherapy, but often develop resistance over time. With increasing use of carboplatin in the… read more here.
Keywords: breast; carboplatin resistant; carboplatin; mitotic checkpoint ... See more keywords
Establishment and Characterization of Carboplatin-Resistant Retinoblastoma Cell Lines
Sign Up to like & getrecommendations! Published in 2022 at "Molecules and Cells"
DOI: 10.14348/molcells.2022.2014
Abstract: Carboplatin-based chemotherapy is the primary treatment option for the management of retinoblastoma, an intraocular malignant tumor observed in children. The aim of the present study was to establish carboplatin-resistant retinoblastoma cell lines to facilitate future… read more here.
Keywords: retinoblastoma; carboplatin; cell lines; resistant retinoblastoma ... See more keywords