Enantioselective Michael addition of 3-ethyl carboxylate substituted pyrazolones to 5-alkenyl thiazolones catalyzed by squaramide organocatalyst
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DOI: 10.1016/j.tetlet.2018.04.083
Abstract: Abstract Asymmetric Michael addition between 3-ethyl carboxylate substituted pyrazolones and 5-alkenylthiazolones catalyzed by a series of chiral bifunctional hydrogen bonding organocatalysts was investigated. Good yields (up to 96%) and excellent enantioselectivities (up to 99% ee)… read more here.
Keywords: carboxylate substituted; addition ethyl; michael addition; substituted pyrazolones ... See more keywords