Ni-Catalyzed Carboxylation of Aziridines en Route to β-Amino Acids.
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DOI: 10.1021/jacs.1c01916
Abstract: A Ni-catalyzed reductive carboxylation of N-substituted aziridines with CO2 at atmospheric pressure is disclosed. The protocol is characterized by its mild conditions, experimental ease, and exquisite chemo- and regioselectivity pattern, thus unlocking a new catalytic… read more here.
Keywords: carboxylation aziridines; amino acids; aziridines route; catalyzed carboxylation ... See more keywords