ASS1-mediated reductive carboxylation of cytosolic glutamine confers ferroptosis resistance in cancer cells.
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DOI: 10.1158/0008-5472.can-22-1999
Abstract: Induction of ferroptosis, a recently defined form of nonapoptotic cell death caused by iron-dependent lipid peroxidation, has emerged as an anti-cancer strategy. Erastin is a ferroptosis activator that promotes cell death that not only depends… read more here.
Keywords: ferroptosis resistance; carboxylation cytosolic; glutamine; cancer ... See more keywords