FETPY: a Diiron(I) Thio-Carbyne Complex with Prominent Anticancer Activity In Vitro and In Vivo.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c00377
Abstract: FETPY, an organo-diiron(I) complex, showed strong cytotoxicity across a panel of human and mouse cancer cell lines, combined with an outstanding selectivity compared to nonmalignant cells. Enhanced iron uptake in aggressive, low-differentiated cell lines, caused… read more here.
Keywords: carbyne complex; thio carbyne; anticancer; diiron thio ... See more keywords
Formal [2 + 2 + 2] Cycloaddition Reaction of a Metal–Carbyne Complex with Nitriles: Synthesis of a Metallapyrazine Complex
Sign Up to like & getrecommendations! Published in 2019 at "Organometallics"
DOI: 10.1021/acs.organomet.9b00213
Abstract: Although alkynes have been extensively exploited in [2 + 2 + 2] cycloadditions with nitriles to form N-heterocyclic aromatics, the “alkyne-like” metal–carbon triple bond has never been used in [2 + 2 + 2] cycloadditions… read more here.
Keywords: cycloaddition; carbyne complex; metal carbyne; complex nitriles ... See more keywords