Three molecular pathways model colorectal carcinogenesis in Lynch syndrome
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DOI: 10.1002/ijc.31300
Abstract: Lynch syndrome is caused by germline mutations of DNA mismatch repair (MMR) genes. MMR deficiency has long been regarded as a secondary event in the pathogenesis of Lynch syndrome colorectal cancers. Recently, this concept has… read more here.
Keywords: colorectal carcinogenesis; carcinogenesis lynch; colorectal cancers; mmr deficiency ... See more keywords