The failure of rodent carcinogenesis as a model for Man.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology research"
DOI: 10.1039/c7tx00283a
Abstract: Recent advances in our understanding of the process of carcinogenesis in Man have required revision of our thinking about the classical initiation/promotion sequence; understanding must now encompass the roles of both genetic and epigenetic change,… read more here.
Keywords: carcinogenesis model; failure rodent; man; rodent carcinogenesis ... See more keywords
The potential of organoids in toxicologic pathology: Histopathological and immunohistochemical evaluation of a mouse normal tissue-derived organoid-based carcinogenesis model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Toxicologic Pathology"
DOI: 10.1293/tox.2022-0021
Abstract: Recently, we introduced an organoid-based chemical carcinogenesis model using mouse normal tissue-derived organoids. In the present review article, the histopathological and immunohistochemical characteristics of mouse normal tissue-derived organoids and tumors derived from these organoids after… read more here.
Keywords: organoid based; normal tissue; pathology; carcinogenesis ... See more keywords
Biliary Tract Carcinogenesis Model Based on Bile Metaproteomics
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.01032
Abstract: Purpose: To analyze human and bacteria proteomic profiles in bile, exposed to a tumor vs. non-tumor microenvironment, in order to identify differences between these conditions, which may contribute to a better understanding of pancreatic carcinogenesis.… read more here.
Keywords: carcinogenesis; carcinogenesis model; biliary tract; pdac group ... See more keywords