In vivo carcinogenicity study of silver nanoparticles in transgenic rasH2 mice by one single-dose intravenous administration
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-020-04836-4
Abstract: Benefited from their broad-spectrum antimicrobial property, silver nanoparticles (AgNPs) have been widely used in various daily life and medical products. Consequently, the bio-safety of AgNPs, especially long-term in vivo biological effects is of more and… read more here.
Keywords: silver nanoparticles; carcinogenicity study; mice; carcinogenicity ... See more keywords
Reevaluation of Hepatocellular Neoplasms in CD-1 Mice from a 2-year Oral Carcinogenicity Study with Permethrin
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DOI: 10.1177/0192623318809304
Abstract: A 24-month oral carcinogenicity study of permethrin was conducted by feeding male and female CD-1 mice diets containing concentrations of 0, 20, 500, and 2,000 ppm of permethrin (males) or 0, 20, 2,500, and 5,000… read more here.
Keywords: carcinogenicity study; oral carcinogenicity; pathology; permethrin ... See more keywords
Regulatory Experience Assessing the Carcinogenic Potential of a Monoclonal Antibody Inhibiting PCSK9, Bococizumab, Including a 2-Year Carcinogenicity Study in Rats
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DOI: 10.1177/10915818221106397
Abstract: Bococizumab is an anti-PCSK9 monoclonal antibody that was intended for the treatment of hypercholesterolemia. After reviewing the 6-month rat toxicity study data, in which there was a low spontaneous tumor incidence, unrelated to bococizumab administration,… read more here.
Keywords: carcinogenicity; year; monoclonal antibody; carcinogenicity study ... See more keywords