Cabozantinib as First-line Treatment in Patients With Metastatic Collecting Duct Renal Cell Carcinoma: Results of the BONSAI Trial for the Italian Network for Research in Urologic-Oncology (Meet-URO 2 Study).
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.0238
Abstract: Importance Metastatic collecting duct carcinoma (mCDC) is a rare type of non-clear cell renal cell carcinoma (ncRCC) with poor prognosis and no standard treatments. Despite retrospective series that have documented the benefit of cabozantinib in… read more here.
Keywords: renal cell; carcinoma; treatment; oncology ... See more keywords
Subacute Abdominal Pain in a Patient With Chronic Liver Disease and Hepatocellular Carcinoma.
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DOI: 10.1001/jamaoncol.2022.3888
Abstract: A 66-year-old woman with chronic hepatitis B infection and hepatocellular carcinoma presented with moderate radiating epigastric pain with nausea, anorexia, and water brash without emesis. What is your diagnosis? read more here.
Keywords: hepatocellular carcinoma; abdominal pain; subacute abdominal; pain patient ... See more keywords
Management of Hepatocellular Carcinoma: A Review.
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DOI: 10.1001/jamasurg.2022.7989
Abstract: Importance Hepatocellular carcinoma (HCC) is the sixth most common malignancy and fourth leading cause of cancer-related death worldwide. Recent advances in systemic and locoregional therapies have led to changes in many guidelines regarding systemic therapy,… read more here.
Keywords: hepatocellular carcinoma; review; disease; association study ... See more keywords
Risk of Squamous Cell Carcinoma of the Breast Following Postmastectomy Implant Reconstruction in Women With Breast Cancer and Carcinoma in Situ.
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DOI: 10.1001/jamasurg.2023.0262
Abstract: This cohort study uses national surveillance data to describe the incidence and risk of squamous cell carcinoma after postmastectomy implant reconstruction in women with breast cancer. read more here.
Keywords: cell carcinoma; postmastectomy implant; squamous cell; implant reconstruction ... See more keywords
Epigallocatechin‐3‐gallate sensitises multidrug‐resistant oral carcinoma xenografts to vincristine sulfate
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DOI: 10.1002/2211-5463.12905
Abstract: Oral squamous cell carcinoma (OSCC) is a very aggressive malignancy, and 50% of patients who receive curative treatment die from the disease or related complications within 5 years. Epigallocatechin‐3‐gallate (EGCG) is the most abundant bioactive… read more here.
Keywords: carcinoma; sensitises multidrug; epigallocatechin gallate; vincristine sulfate ... See more keywords
miR‐30d‐5p suppresses proliferation and autophagy by targeting ATG5 in renal cell carcinoma
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DOI: 10.1002/2211-5463.13025
Abstract: Previous reports have shown that miR‐30d‐5p functions as a tumor suppressor in prostate cancer and gallbladder carcinoma, but its role in renal cell carcinoma (RCC) remains elusive. This study was designed to explore the functional… read more here.
Keywords: carcinoma; rcc; mir 30d; proliferation autophagy ... See more keywords
Hypermethylation of the PZP gene is associated with hepatocellular carcinoma cell proliferation, invasion and migration
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DOI: 10.1002/2211-5463.13093
Abstract: Pregnancy zone protein (PZP), a member of the proteinase inhibitor I39 (‐2‐macroglobulin) family of proteins, is involved in the initiation and development of various tumors. The gene encoding PZP is hypermethylated and expressed at low… read more here.
Keywords: hepatocellular carcinoma; carcinoma; proliferation invasion; hcc ... See more keywords
Population‐based study of the sensitivity of axillary ultrasound imaging in the preoperative staging of node‐positive invasive lobular carcinoma of the breast
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DOI: 10.1002/bjs.10791
Abstract: Preoperative staging of the axilla is important to allow decisions regarding neoadjuvant treatment and the management of the axilla. Invasive lobular carcinoma metastases are difficult to detect because of the infiltrative pattern of the nodal… read more here.
Keywords: study sensitivity; carcinoma; preoperative staging; invasive lobular ... See more keywords
The poor outcome of second primary oral squamous cell carcinoma is attributed to Bmi1 upregulation
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DOI: 10.1002/cam4.1348
Abstract: Radiotherapy for nasopharyngeal carcinoma has been reported to cause second primary oral squamous cell carcinoma (s‐OSCC). The prognosis and pathologic characteristic of s‐OSCC are largely unknown. Bmi1 was associated with the repair of radiation‐induced DNA… read more here.
Keywords: second primary; carcinoma; bmi1 upregulation; primary oral ... See more keywords
ARHGAP42 promotes cell migration and invasion involving PI3K/Akt signaling pathway in nasopharyngeal carcinoma
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DOI: 10.1002/cam4.1552
Abstract: Rho GTPase‐activating protein 42 was identified as an inhibitor of RhoA to maintain normal blood pressure homeostasis. However, the effect of ARHGAP42 in promoting cell malignancy in nasopharyngeal carcinoma is demonstrated in this study. Microarray… read more here.
Keywords: carcinoma; cell migration; arhgap42; nasopharyngeal carcinoma ... See more keywords
The association between methylation patterns of DNAH17 and clinicopathological factors in hepatocellular carcinoma
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DOI: 10.1002/cam4.1930
Abstract: Hepatocellular carcinoma (HCC) is a malignancy with poor prognosis. Complex genetic and epigenetic alterations are the two primary causes of HCC. The aim of the study was mainly to explore the correlation between the methylation… read more here.
Keywords: hepatocellular carcinoma; carcinoma; association methylation; methylation patterns ... See more keywords