Associations between expression levels of nucleotide excision repair proteins in lymphoblastoid cells and risk of squamous cell carcinoma of the head and neck
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22801
Abstract: Squamous cell carcinoma of head and neck (SCCHN) is one of the most common malignancies worldwide, and nucleotide excision repair (NER) is involved in SCCHN susceptibility. In this analysis of 349 newly diagnosed SCCHN patients… read more here.
Keywords: carcinoma head; cell carcinoma; squamous cell; expression ... See more keywords
Phase II trial of combination treatment with S-1/cetuximab in patients with platinum-ineligible recurrent and/or metastatic squamous cell carcinoma of the head and neck
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Clinical Oncology"
DOI: 10.1007/s10147-020-01788-6
Abstract: Background The standard of care for first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) in patients who cannot tolerate platinum-based regimens has not been clarified. We aimed… read more here.
Keywords: metastatic squamous; recurrent metastatic; carcinoma head; cell carcinoma ... See more keywords
Understanding c-MET signalling in squamous cell carcinoma of the head & neck.
Sign Up to like & getrecommendations! Published in 2017 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2017.01.004
Abstract: c-MET is a membrane spanning receptor tyrosine kinase for hepatocyte growth factor (HGF) also termed scatter factor. Transmitting signals from mesenchymal to epithelial cells, the HGF/c-MET axis mediates a range of biological processes that stimulate… read more here.
Keywords: head; carcinoma head; cell carcinoma; squamous cell ... See more keywords
Apoptotic capacity and risk of squamous cell carcinoma of the head and neck.
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DOI: 10.1016/j.ejca.2016.11.018
Abstract: BACKGROUND Tobacco smoke and alcohol drinking are the major risk factors for squamous cell carcinoma of the head and neck (SCCHN). Smoking and drinking cause DNA damage leading to apoptosis, and insufficient apoptotic capacity may… read more here.
Keywords: risk; capacity; carcinoma head; cell carcinoma ... See more keywords
Turning the tide: Clinical utility of PD-L1 expression in squamous cell carcinoma of the head and neck.
Sign Up to like & getrecommendations! Published in 2017 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2017.05.002
Abstract: The use of cytotoxic and/or targeted agents is the gold standard in first- and second-line treatment of metastatic head and neck cancer. Currently the focus of oncologic research is shifting to the implementation of immune… read more here.
Keywords: head; carcinoma head; cell carcinoma; squamous cell ... See more keywords
The role of protein methyltransferases as potential novel therapeutic targets in squamous cell carcinoma of the head and neck
Sign Up to like & getrecommendations! Published in 2018 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2018.04.014
Abstract: Squamous cell carcinoma of the head and neck is a lethal disease with suboptimal survival outcomes and standard therapies with significant comorbidities. Whole exome sequencing data recently revealed an abundance of genetic and expression alterations… read more here.
Keywords: cell carcinoma; squamous cell; carcinoma head; head neck ... See more keywords
Economic burden of chemotherapy-treated recurrent and/or metastatic squamous cell carcinoma of the head and neck in France: real-world data from the permanent sample of national health insurance beneficiaries
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DOI: 10.1080/13696998.2019.1594837
Abstract: Abstract Aims: Overall survival (OS) of patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) is extremely poor. New therapeutic options emerge but need to establish their economic value.… read more here.
Keywords: metastatic squamous; recurrent metastatic; carcinoma head; cell carcinoma ... See more keywords
Indocyanine green dye guided surgical planning in metastatic cutaneous squamous cell carcinoma of the head, face and neck
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DOI: 10.1111/coa.13572
Abstract: Near infrared spectroscopy (NIR) in combination with indocyanine green (ICG) dye can assist surgeons in determining lymph node groups which are likely affected by metastatic cutaneous squamous cell carcinoma of the head, face and neck… read more here.
Keywords: metastatic cutaneous; indocyanine green; carcinoma head; cell carcinoma ... See more keywords
Inhibition of CK2 by CX4945 to induce autophagy-mediated cell death through dephosphorylating acetyl-CoA carboxylase in squamous cell carcinoma of head and neck cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e17503
Abstract: e17503Background: Accumulating evidence has shown that overexpression of casein kinase 2 (CK2) in patients with squamous cell carcinoma of head and neck (SCCHN) correlates with worsened survival. Strong expression of phosphorylated acetyl CoA carboxylase (pACC)… read more here.
Keywords: carcinoma head; cell carcinoma; squamous cell; inhibition ... See more keywords
Response to salvage chemotherapy after progression on immune checkpoint inhibitors in patients with squamous cell carcinoma of the head and neck.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.6015
Abstract: 6015Background: Immune checkpoint inhibitors (ICI) have shown efficacy in patients with recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) with an overall response rate (... read more here.
Keywords: immune checkpoint; checkpoint inhibitors; carcinoma head; cell carcinoma ... See more keywords
89Zr-durvalumab PD-L1 PET in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.3573
Abstract: 3573Background: Immune checkpoint inhibitors (ICI) targeting programmed cell death protein-1/ligand-1 (PD-1/PD-L1) have shown activity in R/M squamous cell carcinoma of the head and neck (SCCHN). P... read more here.
Keywords: carcinoma head; cell carcinoma; squamous cell; cell ... See more keywords