Next-Generation Sequencing for Non-Ampullary Duodenal Carcinoma Suggesting the Existence of an Adenoma-Carcinoma Sequence
Sign Up to like & getrecommendations! Published in 2021 at "Case Reports in Gastroenterology"
DOI: 10.1159/000510919
Abstract: Duodenal tumors with a sporadic adenoma-carcinoma sequence are extremely rare. For such clinically suspected cases without a specific family history, performing a comprehensive gene search is important to understand the germline mutation background. We present… read more here.
Keywords: adenoma; carcinoma; carcinoma sequence; duodenal carcinoma ... See more keywords
Transcriptomic Analyses of the Adenoma-Carcinoma Sequence Identify Hallmarks Associated With the Onset of Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.704531
Abstract: The concept of the adenoma-carcinoma sequence in colorectal cancer (CRC) is widely accepted. However, the relationship between the characteristics of the transcriptome and the adenoma-carcinoma sequence in CRC remains unclear. Here, the transcriptome profiles of… read more here.
Keywords: colorectal cancer; carcinoma sequence; adenoma carcinoma; crc ... See more keywords
The emerging double-edged sword role of Sirtuins in the gastric inflammation-carcinoma sequence revealed by bulk and single-cell transcriptomes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1004726
Abstract: Histone modification and the inflammation-carcinoma sequence (ICS) have been acknowledgedly implicated in gastric carcinogenesis. However, the extremum expression of some histone modification genes (HMGs) in intestinal metaplasia (IM) rather than GC obscures the roles of… read more here.
Keywords: inflammation carcinoma; cell; single cell; cell transcriptomes ... See more keywords
Alteration of the abundance of Parvimonas micra in the gut along the adenoma-carcinoma sequence
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Letters"
DOI: 10.3892/ol.2020.11967
Abstract: Parvimonas micra (P. micra) is reported to be associated with colorectal cancer (CRC). However, its association with colorectal adenoma (CRA) and its role in the initiation of colorectal tumors remain unknown. The present study aimed… read more here.
Keywords: carcinoma sequence; micra; abundance; adenoma carcinoma ... See more keywords