Long Non-Coding RNA LINC01260 Inhibits the Proliferation, Migration and Invasion of Spinal Cord Glioma Cells by Targeting CARD11 Via the NF-κB Signaling Pathway
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DOI: 10.1159/000492279
Abstract: Background/Aims: Spinal cord glioma is a highly aggressive malignancy that commonly results in high mortality due to metastasis, high recurrence and limited treatment regimens. This study aims to elucidate the effects of long non-coding RNA… read more here.
Keywords: linc01260; glioma; invasion; card11 ... See more keywords
Expanding spectrum, intrafamilial diversity, and therapeutic challenges from 15 patients with heterozygous CARD11-associated diseases: A single center experience
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DOI: 10.3389/fimmu.2022.1020927
Abstract: CARD11-associated diseases are monogenic inborn errors of immunity involving immunodeficiency, predisposition to malignancy and immune dysregulation such as lymphoproliferation, inflammation, atopic and autoimmune manifestations. Defects in CARD11 can present as mutations that confer a complete… read more here.
Keywords: card11 associated; card11; associated diseases; spectrum ... See more keywords
Hyper-IgE and Carcinoma in CADINS Disease
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DOI: 10.3389/fimmu.2022.878989
Abstract: Background Atopic dermatitis (AD) affects up to 25% of children and 10% of adults in Western countries. When severe or recurrent infections and exceedingly elevated serum IgE levels occur in AD patients, an inborn error… read more here.
Keywords: carcinoma cadins; cadins disease; hyper ige; ige carcinoma ... See more keywords
A novel CARD11 germline mutation in a Chinese patient of B cell expansion with NF-κB and T cell anergy (BENTA) and literature review
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DOI: 10.3389/fimmu.2022.943027
Abstract: Germline gain-of-function (GOF) mutations in the CARD11 gene lead to a rare primary immunodeficiency disease known as B cell expansion with NF-κB and T cell anergy (BENTA). Affected patients present with a polyclonal expansion of… read more here.
Keywords: cell; germline; cell expansion; card11 ... See more keywords