Inherited CARD9 Deficiency in a Child with Invasive Disease Due to Exophiala dermatitidis and Two Older but Asymptomatic Siblings.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical immunology"
DOI: 10.1007/s10875-021-00988-7
Abstract: PURPOSE Autosomal recessive CARD9 deficiency predisposes patients to invasive fungal disease. Candida and Trichophyton species are major causes of fungal disease in these patients. Other CARD9-deficient patients display invasive diseases caused by other fungi, such… read more here.
Keywords: due exophiala; exophiala dermatitidis; disease; card9 deficiency ... See more keywords
Complete clinical remission of invasive Candida infection with CARD9 deficiency after G-CSF treatment.
Sign Up to like & getrecommendations! Published in 2020 at "Comparative immunology, microbiology and infectious diseases"
DOI: 10.1016/j.cimid.2020.101417
Abstract: Caspase-associated recruitment domain-containing protein 9 (CARD9) deficiency is an autosomal-recessive primary immunodeficiency characterized by susceptibility to recurrent Candida infections, and its diagnosis and treatment is challenging. The present study aims to investigate the genetic characteristic… read more here.
Keywords: card9; treatment; infection; candida ... See more keywords
CARD9 deficiency promotes pancreatic cancer growth by blocking dendritic cell maturation via SLC6A8-mediated creatine transport
Sign Up to like & getrecommendations! Published in 2023 at "Oncoimmunology"
DOI: 10.1080/2162402x.2023.2204015
Abstract: ABSTRACT Pancreatic cancer (PC) is featured with low survival rate and poor outcomes. Herein, we found that the expression of caspase-recruitment domain-containing protein 9 (CARD9), predominantly expressed in innate immune cells, was positively related to… read more here.
Keywords: maturation; card9; card9 deficiency; pancreatic cancer ... See more keywords
CARD9 deficiency predisposing chromoblastomycosis: A case report and comparative transcriptome study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.984093
Abstract: CARD9 mutations are known to predispose patients to phaeohyphomycosis caused by different dematiaceous fungal species. In this study, we report for the first time a patient of chromoblastomycosis caused by Phialophora expanda, who harbored CARD9… read more here.
Keywords: chromoblastomycosis; comparative transcriptome; case; transcriptome study ... See more keywords
[CARD9 Mutation in a Patient with Candida albicans Meningoencephalitis; A Case Report].
Sign Up to like & getrecommendations! Published in 2021 at "Mikrobiyoloji bulteni"
DOI: 10.5578/mb.20219717
Abstract: Primary immunodeficiencies are disorders that cause clinical findings ranging from mild diseases to life-threatening diseases in a wide age range. Infections are the most common complications of primary immunodeficiencies. Caspase associated recruitment domain-9 (CARD9) is… read more here.
Keywords: card9 deficiency; albicans meningoencephalitis; treatment; patient ... See more keywords